A recent case study revealed that a man is reportedly “allergic” to his orgasms as he develops flu-like symptoms after having sex.
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The 27-year-old man, identified as Mr. A, avoided having sex with women due to the flu-like symptoms he developed. In a report by Urology Case Reports, the young man would experience fever, coughing, sneezing, muscle aches, and concentration issues. His ailment is known as Post-Orgasmic Illness Syndrome, a form of sexual dysfunction in men. Additionally, he told doctors that the unusual symptoms began when he was
Dr. Andrew Shanholtzer of Oakland University William Beaumont School of Medicine said in the report that the illness is often misdiagnosed, leading several men to suffer. Currently, there are 60 cases of POIS, and its exact cause is unknown.
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Oddity Central states symptoms begin after an infection or injury to the testicles. This leads to microscopic amounts of sperm leaking into the bloodstream, causing the immune system to respond.
There are special cells called Sertoli cells that nurture and surround sperm and keep it isolated from immune cells. When the Sertoli cells are damaged the sperm is exposed to the immune system for the first time, and the immune system attacks the sperm.
The symptoms last for approximately 2 to 7 days and can randomly end at any time. During a physical exam, doctors treated him with antibiotics and tested him for other allergies.
“Aside from abstaining from sexual activity, the patient was treated with antibiotics without any symptomatic improvement. He had several unremarkable scrotal ultrasounds, a normal semen analysis, and a testosterone level of 421 ng/dL.”
He was given antihistamines for daily treatment to control the symptoms.
“During our initial encounter, we recommended a trial of daily over-the-counter diphenhydramine while gradually increasing the frequency of ejaculation. Additionally, we referred him to an allergist specializing in immunology for possible autologous skin prick testing which has not been performed as of this report due to the COVID-19 pandemic.
Fexofenadine is a relatively safe, inexpensive, and well tolerated medication, but it requires more study in POIS before its therapeutic benefits in this select population can be assessed. Our experience demonstrates the feasibility of treating a complex disease with a simple medication and hopefully will be replicated in future patients.”